Through wide-ranging, and often deeply personal conversation, Oprah Winfrey and Dr. Perry explore how what happens to us in early childhood - both good and bad - influences the people we become. They challenge us to shift from focusing on, "What's wrong with you?" or "Why are you behaving that way?," to asking, "What happened to you?" This simple change in perspective can open up a new and hopeful understanding for millions about why we do the things we do, why we are the way we are, providing a road map for repairing relationships, overcoming what seems insurmountable, and ultimately living better and more fulfilling lives. Many of us experience adversity and trauma during childhood that has lasting impact on our physical and emotional health. And as we're beginning to understand, we are more sensitive to developmental trauma as children than we are as adults. 'What happened to us' in childhood is a powerful predictor of our risk for physical and mental health problems down the road, and offers scientific insights in to the patterns of behaviors so many struggle to understand.