Long Non-coding RNAs in Human Disease

by Kevin V. Morris
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eBook

Publisher: Springer International Publishing

Series: Current Topics in Microbiology and Immunology

Publication Date: May 23, 2016

ISBN: 9783319239071

Binding: Kobo eBook

Availability: eBook

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This volume focuses on the roles of long non-coding RNAs (lncRNAs) in contexts ranging from human cancers to cardiovascular disease and ageing. The role of lncRNAs in X-inactivation and those lncRNAs derived from pseudogenes, past retroelements integrated within the human genome, as well as the role these pseudogene-derived lncRNAs play in cancer development are discussed in detail. Further, the book examines the function of lncRNAs in diseases such as diabetes, in smooth muscle formation, and in the modulation of nuclear receptors, as well as in connection with perspectives on the development of personalized therapeutics. It offers an appealing and insightful resource for scientists and clinicians alike.