This book describes Euthyroid Sick Syndrome, Diagnosis and Treatment and Related Diseases
Euthyroid Sick Syndrome is a disorder featured by abnormal findings of thyroid function tests in the absence of hypothalamic-pituitary and thyroid gland dysfunction.
These abnormal findings in thyroid function test are often linked with disorders such as:
Underlying systemic diseases such as renal diseases, cardiovascular diseases, pulmonary diseases, gastrointestinal diseases etc.
- Metabolic disorders
- Chronic illness such as diabetes
- Inflammatory conditions
- Fasting and starvation
- Burns and sepsis
- Myocardial infarction
- Surgeries such as bone marrow transplantation
In adult patients admitted to a medical service:
- 50% develop a low serum T3 level,
- 15%-20% develop a low T4 level, and
- 10% have an abnormal TSH level (either low or high).
Generally, there are no predisposing genetic or seasonal risk factors.
It is often seen in link with:
- Critical cases in ICU,
- Post cardiopulmonary bypass,
- Renal failure,
- Diabetic ketoacidosis,
- Liver cirrhosis,
The most frequent symptoms and signs happen in acutely ill patients
The symptoms are:
- Hypotonia, and
- Altered mental status.
These features may also happen with hypothyroidism
Euthyroid sick syndrome very often imitates hypothyroidism.
It is a disorder in which the patient normally shows signs of hypothyroidism such as:
- Extreme tiredness or fatigue
- Weight gain
- Disturbed ...