Bayesian Analysis with R for Drug Development

Concepts, Algorithms, and Case Studies
by Harry Yang & Steven Novick
rrp $155.66

Publisher: CRC Press

Series: Chapman & Hall/CRC Biostatistics Series

Publication Date: July 09, 2019

ISBN: 9781351585934

Binding: Kobo eBook

Availability: eBook

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Drug development is an iterative process. The recent publications of regulatory guidelines further entail a lifecycle approach. Blending data from disparate sources, the Bayesian approach provides a flexible framework for drug development. Despite its advantages, the uptake of Bayesian methodologies is lagging behind in the field of pharmaceutical development.

Written specifically for pharmaceutical practitioners, Bayesian Analysis with R for Drug Development: Concepts, Algorithms, and Case Studies,describes a wide range of Bayesian applications to problems throughout pre-clinical, clinical, and Chemistry, Manufacturing, and Control (CMC) development. Authored by two seasoned statisticians in the pharmaceutical industry, the book provides detailed Bayesian solutions to a broad array of pharmaceutical problems.


  • Provides a single source of information on Bayesian statistics for drug development

    Covers a wide spectrum of pre-clinical, clinical, and CMC topics

    Demonstrates proper Bayesian applications using real-life examples

    Includes easy-to-follow R code with Bayesian Markov Chain Monte Carlo performed in both JAGS and Stan Bayesian software platforms

    Offers sufficient background for each problem and detailed description of solutions suitable for practitioners with limited Bayesian knowledge

Harry Yang, Ph.D., is Senior Director and Head of Statistical Sciences at AstraZeneca. He has 24 years of experience across all aspects of drug research and development and extensive global regulatory experiences. He has published 6 statistical books, 15 book chapters, and over 90 peer-reviewed papers on diverse scientific and statistical subjects, including 15 joint statistical works with Dr. Novick. He is a frequent invited speaker at national and international conferences. He also developed statistical courses and conducted training at the ...